Structured Summary
Abstract
The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.
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Synonyms
12 entry terms
- Metabolic Detoxication, Conjugative
- Metabolic Detoxication, Phase II
- Metabolic Detoxification, Phase II
- Phase II Detoxification
- Conjugative Metabolic Detoxication
- Conjugative Metabolic Detoxications
- Detoxication, Conjugative Metabolic
- Detoxications, Conjugative Metabolic
- Detoxification, Phase II
- Detoxifications, Phase II
- Metabolic Detoxications, Conjugative
- Phase II Detoxifications
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Aspects Covered
5 allowable subheadings
Indexed with the subheadings ethnology, genetics, immunology, physiology, radiation effects.
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History Note
2006
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AMA Style
References
- National Library of Medicine. Phase II Metabolic Detoxication. Medical Subject Headings (MeSH). 2026. Unique ID D050217. http://id.nlm.nih.gov/mesh/2026/D050217
- Phase II Metabolic Detoxication. In: Wikidata. https://www.wikidata.org/wiki/Q70578452