Chemicals and Drugs

Tumor Necrosis Factor alpha-Induced Protein 3

A UBIQUITIN editing enzyme that functions as both a ubiquitin ligase and deubiquitinase. It contains several ZINC FINGERS and functions in the immune response and INFLAMMATION by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via TOLL-LIKE RECEPTORS to terminate NF-KAPPA B activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A UBIQUITIN editing enzyme that functions as both a ubiquitin ligase and deubiquitinase. It contains several ZINC FINGERS and functions in the immune response and INFLAMMATION by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via TOLL-LIKE RECEPTORS to terminate NF-KAPPA B activity.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • TNFAIP3 Protein
  • Zinc Finger Protein A20
  • Tumor Necrosis Factor alpha Induced Protein 3

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Cysteine Endopeptidases (2006-2016)
  • DNA-Binding Proteins (2006-2016)
  • Intracellular Signaling Peptides and Proteins (2006-2016)
  • Nuclear Proteins (1992-2016)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.037w.750.500
  2. D08.811w.277w.656w.300w.887.750
  3. D08.811w.464w.938.750.813
  4. D12.644w.360.950
  5. D12.776w.476.938

AMA Style

References

  1. National Library of Medicine. Tumor Necrosis Factor alpha-Induced Protein 3. Medical Subject Headings (MeSH). 2026. Unique ID D000072598. http://id.nlm.nih.gov/mesh/2026/D000072598
  2. Tumor Necrosis Factor alpha-Induced Protein 3. In: Wikidata. https://www.wikidata.org/wiki/Q24786915