Phenomena and Processes

ras Genes

Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

97 entry terms
  • Genes, ras
  • ras Gene
  • H-ras Genes
  • H-ras Oncogenes
  • Ha-ras Genes
  • Ha-ras Oncogenes
  • K-ras Genes
  • K-ras Oncogenes
  • Ki-ras Genes
  • Ki-ras Oncogenes
  • N-ras Genes
  • N-ras Oncogenes
  • c-H-ras Genes
  • c-H-ras Proto-Oncogenes
  • c-Ha-ras Genes
  • c-Ha-ras Proto-Oncogenes
  • c-K-ras Genes
  • c-K-ras Proto-Oncogenes
  • c-Ki-ras Genes
  • c-Ki-ras Proto-Oncogenes
  • c-N-ras Genes
  • c-N-ras Proto-Oncogenes
  • ras Oncogene
  • v-H-ras Genes
  • v-H-ras Oncogenes
  • v-Ha-ras Genes
  • v-Ha-ras Oncogenes
  • v-K-ras Genes
  • v-K-ras Oncogenes
  • v-Ki-ras Genes
  • v-Ki-ras Oncogenes
  • Gene, Ha-ras
  • Gene, Ki-ras
  • Gene, v-Ha-ras
  • Gene, v-Ki-ras
  • Genes, Ha-ras
  • Genes, Ki-ras
  • Genes, N-ras
  • Genes, v-Ha-ras
  • Genes, v-Ki-ras
  • H ras Genes
  • H ras Oncogenes
  • H-ras Gene
  • H-ras Oncogene
  • Ha ras Genes
  • Ha ras Oncogenes
  • Ha-ras Gene
  • Ha-ras Oncogene
  • K ras Genes
  • K ras Oncogenes
  • K-ras Gene
  • K-ras Oncogene
  • Ki ras Genes
  • Ki ras Oncogenes
  • Ki-ras Gene
  • Ki-ras Oncogene
  • N ras Genes
  • N ras Oncogenes
  • N-ras Gene
  • N-ras Oncogene
  • c H ras Genes
  • c H ras Proto Oncogenes
  • c Ha ras Genes
  • c Ha ras Proto Oncogenes
  • c K ras Genes
  • c K ras Proto Oncogenes
  • c Ki ras Genes
  • c Ki ras Proto Oncogenes
  • c N ras Genes
  • c N ras Proto Oncogenes
  • c-H-ras Gene
  • c-H-ras Proto-Oncogene
  • c-Ha-ras Gene
  • c-Ha-ras Proto-Oncogene
  • c-K-ras Gene
  • c-K-ras Proto-Oncogene
  • c-Ki-ras Gene
  • c-Ki-ras Proto-Oncogene
  • c-N-ras Gene
  • c-N-ras Proto-Oncogene
  • ras Oncogenes
  • v H ras Genes
  • v H ras Oncogenes
  • v Ha ras Genes
  • v Ha ras Oncogenes
  • v K ras Genes
  • v K ras Oncogenes
  • v Ki ras Genes
  • v Ki ras Oncogenes
  • v-H-ras Gene
  • v-H-ras Oncogene
  • v-Ha-ras Gene
  • v-Ha-ras Oncogene
  • v-K-ras Gene
  • v-K-ras Oncogene
  • v-Ki-ras Gene
  • v-Ki-ras Oncogene

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

1991; was RAS GENES 1988-1990; was RAS GENES see ONCOGENES 1985-1987

MeSH Record

Previous Indexing

  • Genes, Viral (1978-1987)
  • Oncogenes (1983-1987)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QZ 210

AMA Style

References

  1. National Library of Medicine. ras Genes. Medical Subject Headings (MeSH). 2026. Unique ID D011905. http://id.nlm.nih.gov/mesh/2026/D011905
  2. ras Genes. In: Wikidata. https://www.wikidata.org/wiki/Q60039439