Chemicals and Drugs

ras Proteins

Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein ONCOGENE PROTEIN P21(RAS) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein ONCOGENE PROTEIN P21(RAS) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47.

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Synonyms

8 entry terms
  • Gene Products, ras
  • ras GTPase
  • ras GTPases
  • ras Protein
  • GTPase, ras
  • GTPases, ras
  • Protein, ras
  • ras Gene Products

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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Indexing Annotation

ras derived from "Rat Sarcoma"

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History Note

95

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Tree Numbers

  1. D08.811w.277w.040w.330.300.400.500w
  2. D12.776w.157w.325.515.500w
  3. D12.776w.476.338.400.500w

AMA Style

References

  1. National Library of Medicine. ras Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D018631. http://id.nlm.nih.gov/mesh/2026/D018631
  2. ras Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/Ras_GTPase
  3. ras Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q424396