Structured Summary
Abstract
Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumors. This enzyme was formerly listed as EC 3.6.1.47.
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Synonyms
20 entry terms
- p21 Transforming Viral Protein
- p21 v-H-ras
- p21 v-Ha-ras
- p21 v-Ki-ras
- p21 v-ras
- p21(v-H-ras)
- p21(v-Ha-ras)
- p21(v-K-ras)
- p21(v-Ki-ras)
- ras Oncogene Product p21
- ras Oncogene Protein p21
- ras Oncogene p21 Product
- p21 v H ras
- p21 v Ha ras
- p21 v Ki ras
- p21 v ras
- v-H-ras, p21
- v-Ha-ras, p21
- v-Ki-ras, p21
- v-ras, p21
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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Indexing Annotation
coord with specific virus
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History Note
1990
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Previous Indexing
- Neoplasm Proteins (1980-1986)
- Oncogene Proteins, Viral (1986-1989)
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AMA Style
References
- National Library of Medicine. Oncogene Protein p21(ras). Medical Subject Headings (MeSH). 2026. Unique ID D015689. http://id.nlm.nih.gov/mesh/2026/D015689
- Oncogene Protein p21(ras). In: Wikidata. https://www.wikidata.org/wiki/Q78188426