Structured Summary
Abstract
The largest subunit of the anaphase-promoting complex. It acts primarily as a scaffold for the proper organization and arrangement of subunits. The C-terminal region of Apc1 contains a series of tandem amino acid repeats that are also seen in the 26S proteasome regulatory particle, and may assist with forming and stabilizing protein-protein interactions.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
5 entry terms
- Anapc1
- Apc1 Subunit, Anaphase-Promoting Complex
- Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome
- Apc1 Subunit, Anaphase Promoting Complex
- Apc1 Subunit, Anaphase Promoting Complex Cyclosome
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2014
MeSH Record
Previous Indexing
- Cell Cycle Proteins (1996-2003)
- Ligases (1996-2003)
- Ubiquitin-Protein Ligase Complexes (2004-2013)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Anaphase-Promoting Complex-Cyclosome Apc1 Subunit. Medical Subject Headings (MeSH). 2026. Unique ID D064189. http://id.nlm.nih.gov/mesh/2026/D064189
- Anaphase-Promoting Complex-Cyclosome Apc1 Subunit. In: Wikidata. https://www.wikidata.org/wiki/Q24777395