Chemicals and Drugs

CD11c Antigen

An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.

MeSH Record

Classification

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MeSH Record

Synonyms

8 entry terms
  • Antigens, CD11c
  • CD11c Antigens
  • Integrin alphaX
  • Leu-M5 Antigens
  • Antigen, CD11c
  • Antigens, Leu-M5
  • Leu M5 Antigens
  • alphaX, Integrin

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2018 (1995); for CD11C ANTIGEN and ANTIGENS, CD11C use INTEGRIN ALPHAXBETA2 1995-2002

MeSH Record

Previous Indexing

  • Integrin alphaXbeta2 (1995-2002)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. CD11c Antigen. Medical Subject Headings (MeSH). 2026. Unique ID D039521. http://id.nlm.nih.gov/mesh/2026/D039521
  2. CD11c Antigen. In: Wikidata. https://www.wikidata.org/wiki/Q77839150